Ernie Davis
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Ernie Davis, the first African-American to win the Heisman Trophy was diagnosed with acute monocytic leukemia at the age of 22 and died May 18, 1963 at the age of 23.

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** FILE ** RB Ernie Davis, Syracuse (1962, 1st) - One of just two No. 1 overall picks Redskins have had, he was traded to the Browns for WR Bobby Mitchell (among others) and died of leukemia in 1963.